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Celebrities Are Getting Salmon Sperm Facials, and the Science Checks Out : The Hearty Soul


Over many years, celebrities and beauty influencers have engaged in some unusual skin treatment trends, or just health care trends in general. Those interested in skincare trends will remember Kim Kardashian’s bloodied-face after the infamous “vampire facial” or the viral “snail mucus” beauty serum. In their pursuit of preserving youthful looks, Hollywood celebrities have begun embracing the latest anti-aging trend: salmon sperm facials.

Jennifer Aniston, Kim Kardashian, and Miley Cyrus openly endorse these bizarre treatments for radiant and youthful-looking skin. However strange, salmon sperm facials are actually validated by scientific research. While the naming might be unconventional, salmon sperm facials or “polynucleotide treatments” possess potent regenerative properties. Delve into why celebrities are quickly hopping onto this trend, its benefits and the science behind how it works.

The Celebrity Endorsement Boom

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Jennifer Aniston first mentioned salmon sperm facials in a 2023 Wall Street Journal interview. As per her aesthetician’s advice and recommendation, she got a salmon sperm facial. However, she told WSJ she was unsure whether the treatment actually “did anything”. Kim Kardashian later showcased the treatment on her reality show The Kardashians, discussing the facial with her mother, Kris Jenner. 

Miley Cyrus is one of the most recent A-lister that raves about its effectiveness. During a New York performance, a fan in the crowd complimented Cyrus on her skin. She then joked about its “strange taste” but praised its results. Their endorsements propelled this Korean beauty secret into mainstream consciousness. Clinical studies now support their claims, bridging celebrity hype with scientific credibility.

What Salmon Sperm Facials Actually Involve

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Salmon sperm facials or “polynucleotide treatments” use polynucleotides (PDRN), which are DNA fragments extracted from salmon sperm. The sperm undergoes rigorous purification to isolate the regenerative compounds in the sperm to use for the facial. When the treatment is administered, providers inject PDRN directly into facial tissue or apply it topically after microneedling. 

This process stimulates collagen production, which promotes cellular repair. The treatment also stimulates the production of keratinocytes and new blood vessels which in conjunction with collagen, promotes new skin cells. No raw salmon sperm is applied, providers only administer laboratory-processed biomolecules, which drive its regenerative effects. The treatment focuses on skin rejuvenation at a molecular level.

PDRN activates adenosine A2A receptors, triggering 3 key processes. First, it hinders inflammation-causing cytokines. Second, it boosts collagen and elastin synthesis. Third, it accelerates tissue regeneration through new blood vessel formation. A 2022 review in the Chinese Journal of Plastic and Reconstructive Surgery confirmed PDRN improves elasticity and hydration. Another 2024 study noted visible scar reduction in burn patients.

Read More: Celebrity-Endorsed ‘Brain Fuel’ Pill Sparks Doctor Warnings

Evidence-Backed Anti-Aging Benefits

Woman Having Cosmetic Treatment
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Clinical trials demonstrate measurable improvements from salmon sperm facials. Participants saw 25% fewer fine lines and 30% better hydration after treatments. Collagen production had increased by 40% in UV-damaged skin. The polynucleotides also repair sun damage and reduce hyperpigmentation. Unlike temporary fillers, these changes result from cellular regeneration. Results typically last 3-6 months per session.

Step-by-Step Treatment Experience

Woman during Facial Treatment
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Patients first undergo a skin analysis to customize PDRN concentration. A numbing cream is applied before microneedling or injections. The procedure takes around 60-90 minutes and causes mild redness. Most people require 2-4 sessions spaced monthly to receive its full effects. Post-care treatment involves avoiding sun exposure and harsh products for at least 48 hours after the procedure. Gradual improvements appear within weeks as collagen rebuilds. 

Read More: 9 Natural Ways To Improve Dry Flaky Skin

Cost and Regulatory Considerations

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This internet viral facial with scientific backing does come with a hefty price tag. Expect to pay  $300-$600 for each session, with full recommended packages reaching approximately $2,400. Korean clinics use injectable PDRN, while U.S. providers favor topical applications due to FDA restrictions. The treatment is approved in South Korea and Singapore but not by the FDA or Australia’s TGA. Ethical concerns exist regarding animal-derived ingredients. Allergic reactions are possible for those with seafood sensitivities.

Safety Profile and Potential Risks

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Common side effects include temporary redness, swelling, and bruising. In rare cases, patients report headaches or nausea. No severe complications have been documented in peer-reviewed studies. However, dermatologists like Dr. Hadley King urge caution pending long-term safety data. Patch tests are recommended before pursuing full treatments. Dermatologists advise you to avoid this treatment if you are pregnant or are allergic to seafood.

Read More: 8 Beauty Benefits of Ginger for Glowing Skin and Hair

Comparison to Botox and Fillers

Woman Getting a Face Botox
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Botox paralyzes muscles to smooth wrinkles but does not promote cellular regeneration  and collagen production. Fillers add volume but require frequent touch-ups to maintain. Salmon sperm facials work differently: they stimulate natural collagen and repair cellular damage. Results appear gradually rather than instantly. Combined treatments exist, like PDRN with hyaluronic acid for enhanced hydration. Each approach suits different anti-aging goals.

Making an Informed Decision

A Woman Looking at the Mirror while Applying a Cream on Her Face
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Salmon sperm facials offer scientifically backed benefits but are not miracle solutions. Ideal candidates seek collagen boosting without surgery. Avoid pursuing this treatment if you prefer vegan products or are looking for instant fixes and results. Also avoid this treatment if you have seafood allergies and if you are pregnant. Consult board-certified dermatologists before going forward with salmon sperm facials. As research evolves, this treatment may become mainstream. For now, it remains a high-end option with compelling evidence. 

Read More: Here’s Why You See So Many Celebrities Wearing Red Lens Glasses



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